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Items: 4

1.

Pyruvate dehydrogenase complex integrates the metabolome and epigenome in memory CD8+ T cell differentiation in vitro

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platform:
GPL24247
37 Samples
Download data: BEDGRAPH, BROADPEAK, BW, NARROWPEAK, RESULTS
Series
Accession:
GSE231556
ID:
200231556
2.

Pyruvate dehydrogenase complex integrates the metabolome and epigenome in memory CD8+ T cell differentiation in vitro [RNA-Seq]

(Submitter supplied) Modulation of metabolic flux through pyruvate dehydrogenase complex (PDC) plays an important role in T cell activation and differentiation. PDC sits at the transition between glycolysis and the tricarboxylic acid cycle and is a major producer of acetyl-CoA, marking it as a potential metabolic and epigenetic node. To understand the role of pyruvate dehydrogenase complex in T cell differentiation, we generated mice deficient in T cell pyruvate dehydrogenase E1A (Pdha) subunit using a CD4-cre recombinase-based strategy. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
16 Samples
Download data: RESULTS
Series
Accession:
GSE231553
ID:
200231553
3.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
4.

HHV57DSXY_19005478_S46,TT16_A,PDH_MEMORY

Organism:
Mus musculus
Source name:
MEMORY
Platform:
GPL24247
Series:
GSE231553 GSE231556
Download data: RESULTS
Sample
Accession:
GSM7290703
ID:
307290703
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Supplemental Content

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