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Items: 3

1.

Bacterial TLR2/6 Ligands Block Ciliogenesis, Derepress Hedgehog Signaling, and Expand the Neocortex

(Submitter supplied) Microbial components have a range of direct effects on the fetal brain. However, little is known about the cellular targets and molecular mechanisms that mediate these effects. Neural progenitor cells (NPCs) control the size and architecture of the brain and understanding the mechanisms regulating NPCs is crucial to understanding brain developmental disorders. We identify ventricular radial glia (vRG), the primary NPC, as the target of bacterial cell wall (BCW) generated during the antibiotic treatment of maternal pneumonia. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Other
Platform:
GPL24247
8 Samples
Download data: H5, JSON, TIFF
Series
Accession:
GSE229699
ID:
200229699
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

Mouse brain spatial transcriptomics, E12, ampicillin control, replicate 3

Organism:
Mus musculus
Source name:
embryonic brain
Platform:
GPL24247
Series:
GSE229699
Download data: H5, JSON, TIFF
Sample
Accession:
GSM7173408
ID:
307173408
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