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Items: 3

1.

High-throughput sensitive screening of small molecule modulators of microexon alternative splicing using dual Nano and Firefly luciferase reporters

(Submitter supplied) Disruption of alternative splicing frequently causes or contributes to human diseases and disorders. Consequently, there is a need for efficient and sensitive reporter assays capable of screening chemical libraries for compounds with efficacy in modulating important splicing events. Here, we describe a screening workflow employing dual Nano and Firefly luciferase alternative splicing reporters that affords highly efficient, sensitive, and linear detection of small molecule responses. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
34 Samples
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Series
Accession:
GSE228599
ID:
200228599
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

N2A cells, Vorinostat_SAHA, replicate A

Organism:
Mus musculus
Source name:
N2A
Platform:
GPL24247
Series:
GSE228599
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Sample
Accession:
GSM7133770
ID:
307133770
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