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Items: 4

1.

Aberrant cell state plasticity mediated by developmental reprogramming precedes colorectal cancer initiation [scRNA-seq]

(Submitter supplied) Cell state plasticity is carefully regulated in adult epithelia, enabling adaptive responses to stressors. The nongenetic factors that control aberrant expansion of the normally restricted capability for cell state plasticity to escape terminal differentiation in neoplasia require deeper characterization. Using genetically-engineered and carcinogen-induced murine models of intestinal neoplasia, we demonstrate that impaired differentiation is a conserved event preceding cancer development. more...
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL19057 GPL18573
9 Samples
Download data: MTX, TSV
Series
Accession:
GSE224679
ID:
200224679
2.

Aberrant cell state plasticity mediated by developmental reprogramming precedes colorectal cancer initiation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
19 Samples
Download data: BIGWIG, BW, MTX, TSV
Series
Accession:
GSE221300
ID:
200221300
3.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
4.

Day 10

Organism:
Mus musculus
Source name:
Intestine
Platform:
GPL19057
Series:
GSE221300 GSE224679
Download data: MTX, TSV
Sample
Accession:
GSM7029392
ID:
307029392
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Supplemental Content

db=gds|term=GSM7029392[Accession]|query=1|qty=3|blobid=MCID_67016e81d3e79154ac40fbe0|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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