GEO DataSets

(Submitter supplied) Pancreatic ductal adenocarcinoma (PDAC) tumors carry multiple gene mutations and respond poorly to treatments. There is currently an unmet need for drug carriers that can deliver multiple gene cargoes to high solid tumor burden like PDAC. Here, we report a dual-targeted extracellular vesicle (EV) carrying high loads of RNA that effectively suppresses large PDAC tumors in mice. The EV surface contains a CD64 protein that has a tissue targeting peptide and a humanized monoclonal antibody. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL16699

15 Samples

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(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:

Mus musculus; Homo sapiens

Type:

Non-coding RNA profiling by high throughput sequencing; Expression profiling by array

4 related Platforms

43 Samples

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(Submitter supplied) SurePrint G3 Human GE v2 8x60K Microarray Design ID: 039494 Design Format: 8 x 60 K Control Grid: IS-62976-8-V2_60kby8_GX_EQC_201000210 Build Version: hg19:GRCh37:Feb2009 Arrays of this design have barcodes that begin with 16039494 or 2539494. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. more...

Organism:

Homo sapiens

311 Series

1 Related Platform

3972 Samples

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