GSM6879760[Accession] - GEO DataSets

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Items: 4

Select item 2002215191.

BRWD1 orchestrates chromatin topology by converting static to dynamic cohesin complexes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Other

Platforms:: GPL21103 GPL24247
46 Samples

Download data: BED, BW, HIC

Series

Accession:: GSE221519

ID:: 200221519

PubMed Similar studies

Select item 2002215182.

BRWD1 orchestrates chromatin topology by converting static to dynamic cohesin complexes (ChIP-Seq)

(Submitter supplied) Lymphocyte development consists of sequential and mutually exclusive cell states of proliferative selection and antigen receptor gene recombination. Transitions between each state require large, coordinated changes in epigenetic landscapes and transcriptional programs. How this occurs remains unclear. Herein, we demonstrate that in small pre-B cells, the lineage and stage-specific epigenetic reader BRWD1 reorders three-dimensional chromatin topology to affect transition between proliferative and gene recombination molecular programs. more...