GSM6671886[Accession] - GEO DataSets

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Items: 4

Select item 2002163911.

Engineered T cell therapy for central nervous system injury

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus; Homo sapiens

Type:: Expression profiling by high throughput sequencing; Other

Platforms:: GPL24247 GPL19057 GPL18573
230 Samples

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Series

Accession:: GSE216391

ID:: 200216391

Select item 2002163892.

Engineered T cell therapy for central nervous system injury [CD45+ scRNA-seq]

(Submitter supplied) Traumatic injuries to the central nervous system (CNS) affect millions of people worldwide yet lack an effective treatment. These injuries contain infiltrating immune cells that can promote tissue repair and could be exploited for therapeutic benefit. Here, using single-cell RNA-sequencing of T cells infiltrating the injured CNS we demonstrate their clonal expansion and antigen specificity towards CNS derived self-peptides. more...