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Items: 4

1.

Epigenetic dysregulation from chromosomal transit in micronuclei [DLD-1 CUT&RUN]

(Submitter supplied) Chromosomal instability (CIN) and epigenetic reprograming are characteristic of advanced and metastatic human cancers, yet whether they are mechanistically linked is unknown. Here we show that missegregation of mitotic chromosomes, their sequestration in micronuclei, and subsequent micronuclear envelope rupture significantly disrupt normal histone post-translational modifications, a phenomenon conserved across humans and mice as well as cancer and non-transformed cells. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL30173
90 Samples
Download data: BW
Series
Accession:
GSE214012
ID:
200214012
2.

Epigenetic dysregulation from chromosomal transit in micronuclei

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
5 related Platforms
187 Samples
Download data: BED, BIGWIG, BW, TDF, TXT
Series
Accession:
GSE186589
ID:
200186589
3.

NextSeq 2000 (Homo sapiens)

Platform
Accession:
GPL30173
ID:
100030173
4.

DLD-1 cln9 H3K27me3 biol rep 1

Organism:
Homo sapiens
Source name:
DLD-1 Cells
Platform:
GPL30173
Series:
GSE186589 GSE214012
Download data: BW
Sample
Accession:
GSM6597786
ID:
306597786
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Supplemental Content

db=gds|term=GSM6597786[Accession]|query=1|qty=3|blobid=MCID_66df22353ec0504f94213ce4|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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