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Items: 3

1.

Modular oxidation of cytosine modifications and their application in direct and quantitative sequencing of 5-hydroxymethylcytosine

(Submitter supplied) Selective, efficient, and controllable oxidation of cytosine modifications is valuable for epigenetic analyses, yet only limited progress has been made. Here, we present two modular chemical oxidation reactions: conversion of 5-hydroxymethylcytosine (5hmC) into 5-formylcytosine (5fC) utilizing 4-acetamido-2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate (ACT+ BF4–) and further transformation of 5fC into 5-carboxycytosine (5caC) through Pinnick oxidation. more...
Organism:
Homo sapiens; Mus musculus
Type:
Methylation profiling by high throughput sequencing
Platforms:
GPL30173 GPL30172
4 Samples
Download data: BEDGRAPH
Series
Accession:
GSE214006
ID:
200214006
2.

NextSeq 2000 (Homo sapiens)

Platform
Accession:
GPL30173
ID:
100030173
3.

tumor brain, CAPS+

Organism:
Homo sapiens
Source name:
brain
Platform:
GPL30173
Series:
GSE214006
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Sample
Accession:
GSM6597703
ID:
306597703
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