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Items: 3

1.

Single-cell transcriptomics of resected human traumatic brain injury tissues reveals acute activation of endogenous retroviruses in oligodendroglia

(Submitter supplied) Traumatic brain injury (TBI) is a leading cause of chronic brain impairment and results in a robust, but poorly understood, neuroinflammatory response that contributes to the long-term pathology. We used snRNA-seq to study transcriptomic changes in different cell populations in human brain tissue obtained acutely after severe, life-threatening TBI. This revealed a unique transcriptional response in oligodendrocyte precursors and mature oligodendrocytes, including the activation of a robust innate immune response, indicating an important role for oligodendroglia in the initiation of neuroinflammation. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24676 GPL18573
30 Samples
Download data: BW, CSV, MTX, TSV
Series
Accession:
GSE209552
ID:
200209552
2.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
3.

TBI 1, scRNAseq

Organism:
Homo sapiens
Source name:
brain
Platform:
GPL24676
Series:
GSE209552
Download data: CSV, MTX, TSV
Sample
Accession:
GSM6376820
ID:
306376820
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db=gds|term=GSM6376820[Accession]|query=1|qty=2|blobid=MCID_67b385c01a48797f60a4cac4|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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