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Items: 3

1.

Effects of DAC treatment

(Submitter supplied) Reversal of gene promoter DNA hypermethylation and associated abnormal gene silencing is an attractive approach to cancer therapy. The DNA methylation inhibitor, decitabine (5-aza-2'-deoxycitidine), is proving efficacious for hematological neoplasms especially at lower, less toxic, doses. Experimentally, high doses induce rapid DNA damage and cytotoxicity, but these may not explain the prolonged time to response seen in patients. more...
Organism:
Homo sapiens
Type:
Expression profiling by array; Methylation profiling by array
4 related Platforms
55 Samples
Download data: TXT
Series
Accession:
GSE20945
ID:
200020945
2.

Illumina HumanMethylation27 BeadChip (HumanMethylation27_270596_v.1.2)

(Submitter supplied) HumanMethylation27 DNA Analysis BeadChip allows researchers to interrogate 27,578 highly informative CpG sites per sample at single-nucleotide resolution. This 12-sample BeadChip features content derived from the well-annotated NCBI CCDS database (Genome Build 36) and is supplemented with more than 1,000 cancer-related genes described in published literature. Probe content has been enriched to deeply cover more than 150 well-established cancer genes known to show differential methylation patterns. more...
Organism:
Homo sapiens
348 Series
19058 Samples
Download data: CSV
Platform
Accession:
GPL8490
ID:
100008490
3.

Primary Leukemia - Untreated - Patient 4 [CH3'n profiling]

Organism:
Homo sapiens
Source name:
Primary leukemia
Platform:
GPL8490
Series:
GSE20945
Download data
Sample
Accession:
GSM618229
ID:
300618229
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db=gds|term=GSM618229[Accession]|query=1|qty=2|blobid=MCID_65dce129a642ff6770cc92fa|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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