GSM6030615[Accession] - GEO DataSets

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Items: 4

Select item 2002003041.

A genome-wide functional study of 3’UTR mutations in advanced prostate cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Other; Expression profiling by high throughput sequencing

Platforms:: GPL30173 GPL16791
55 Samples

Download data: TXT

Series

Accession:: GSE200304

ID:: 200200304

PubMed Full text in PMC Similar studies

Select item 2002003022.

A genome-wide functional study of 3’UTR mutations in advanced prostate cancer [Polysome-Seq]

(Submitter supplied) Metastatic, castration-resistant prostate cancer (mCRPC) is an advanced form of prostate cancer with a high mortality rate due to a current lack of treatment options. While much is already known about how mutations in protein-coding sequences across the genome affect prostate cancer, somatic mutations occurring in the 3’ untranslated regions (3’UTRs) of genes are largely unstudied. The 3’UTR is a genomic region that controls post-transcriptional gene expression through its recruitment of trans-acting factors such as RNA-binding proteins (RBPs) and microRNAs (miRNAs), which themselves are known to be oncogenes and tumor suppressors in many cases. more...