GSM5973991[Accession] - GEO DataSets

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Items: 4

Select item 2001994821.

Divergent transcriptional regulation of astrocyte reactivity across disorders

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL24247
41 Samples

Download data: BED, H5, MTX, TSV

Series

Accession:: GSE199482

ID:: 200199482

PubMed Full text in PMC Similar studies

Select item 2001994812.

Divergent transcriptional regulation of astrocyte reactivity across disorders [TR_ATAC_SCI]

(Submitter supplied) Single-nuclei Assay for Transposase-Accessible Chromatin with sequencing (snATACseq) was applied to examine chromatin landscape changes and transcriptional regulator (TR) DNA motif accessibility in reactive astrocytes following traumatic spinal cord injury (SCI). Astrocyte nuclei were isolated from the spinal cord of wild type mice and mice with astrocyte-specific conditional gene deletion (cKO) of test-case TRs, SMARCA4 (Smarca4-astro-cKO) or STAT3 knockout (Stat3-astro-cKO). more...