GSM5964788[Accession] - GEO DataSets

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Items: 4

Select item 2001991661.

Stress signaling boosts interferon-induced gene transcription in macrophages

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL21493 GPL24247
90 Samples

Download data: BW, NARROWPEAK

Series

Accession:: GSE199166

ID:: 200199166

PubMed Similar studies

Select item 2001991272.

c-Jun and CREB1 transcription factor binding analysis in wild type bone marrow-derived macrophages in response to type II interferon and stress

(Submitter supplied) The innate immune system acts as the first line of defense against invasion of microbial pathogens. Here, macrophages play a substantial role in recognition, phagocytosis and killing of pathogens and the regulation of the innate immune response. Here, interferons play a crucial role in augmenting the antimicrobial functions of macrophages and their ability to produce mediators of immunoregulation. Pathogen recognition activates many different signaling pathways that interact to produce an innate response commensurate with the microbial challenge. more...