GSM5940185[Accession] - GEO DataSets

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Items: 4

Select item 2001981821.

A de novo transcription-dependent TAD boundary underpins critical multiway interactions during antibody class switch recombination

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Other

Platforms:: GPL17021 GPL24247
69 Samples

Download data: BW, MCOOL, TAB

Series

Accession:: GSE198182

ID:: 200198182

PubMed Similar studies

Select item 2001981812.

A de novo transcription-dependent TAD boundary underpins critical multiway interactions during antibody class switch recombination [Micro-C]

(Submitter supplied) Antibody class switch recombination (CSR) requires the ligation of DNA breaks in transcribed and juxtaposed donor and acceptor switch (S) sequences (S-S synapsis) spaced 50-200 kb apart within the immunoglobulin heavy chain locus (Igh). CSR is believed to occur via the association of active S regions with the 3’ regulatory region (3’RR) super-enhancer thereby coupling transcription with S-S synapsis. more...