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Items: 3

1.

A satellite DNA array barcodes chromosome 7 and regulates totipotency via ZFP819

(Submitter supplied) Mammalian genomes are a battleground for genetic conflict between repetitive elements (REs) and KRAB-zinc finger proteins (KZFPs). We explored whether KZFPs can regulate cell fate by employing Zfp819, which targets a satellite DNA array, ZP3AR. ZP3AR coats a megabase region of chromosome 7 that encompasses genes encoding ZSCAN4, a master transcription factor of totipotency. Depleting Zfp819 in mouse embryonic stem cells (mESCs) causes them to transition to a 2-cell (2C)-like state, whereby the ZP3AR array switches from a poised to an active enhancer state. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL19057 GPL24247 GPL17021
43 Samples
Download data: BED, BW, XLSX
Series
Accession:
GSE197548
ID:
200197548
2.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
3.

ZFP809_IP2

Organism:
Mus musculus
Source name:
mESC
Platform:
GPL17021
Series:
GSE197548
Download data
Sample
Accession:
GSM5920471
ID:
305920471
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db=gds|term=GSM5920471[Accession]|query=1|qty=2|blobid=MCID_672e9694198554024938e264|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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