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Items: 3

1.

LGR5 expressing skin fibroblasts define a major hub perturbed in Systemic Sclerosis

(Submitter supplied) Systemic sclerosis (SSc) is an incurable autoimmune disease with high morbidity and mortality rates, with no effective treatment. Here, we conducted a population scale single-cell genomic analysis of skin and blood samples of 56 healthy controls, and 97 SSc patients at different stages of disease. We found immune compartment activation in only a subset of diffuse SSc patients, but global dysregulation of the stromal compartment, including a novel subset of LGR5+ scleroderma associated fibroblasts (ScAF). more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL18573 GPL24676
727 Samples
Download data: TAR, TXT
Series
Accession:
GSE195452
ID:
200195452

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NovaSeq 6000 (Homo sapiens)

Organism:
Homo sapiens
16543 Series
922800 Samples
Download data
Platform
Accession:
GPL24676
ID:
100024676

3.

Healthy_multiome_atac

Organism:
Homo sapiens
Source name:
Forearm skin atac-seq
Platform:
GPL24676
Series:
GSE195452
Download data: TAR
Sample
Accession:
GSM5884742
ID:
305884742

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db=gds|term=GSM5884742[Accession]|query=1|qty=2|blobid=MCID_67058f4c1979ea5df8313fa4|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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