GSM5832927[Accession] - GEO DataSets

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Items: 4

Select item 2001956111.

3D chromatin architecture of drug-tolerant cancer cells at single-cell resolution

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL21290 GPL24676
410 Samples

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Accession:: GSE195611

ID:: 200195611

PubMed

Select item 2001943082.

3D chromatin architecture of drug-tolerant cancer cells at single-cell resolution [scHi-C]

(Submitter supplied) Anticancer drug therapy generally elicits the drug tolerance after long-term treatment. Recent studies suggested that 3D chromatin structures of cancer cells were intimately linked to drug resistance. However, 3D chromatin structures in drug-tolerant cancer cells at single-cell resolution haven’t been elucidated. Here we performed single-cell Hi-C (scHi-C) analysis to examine the 3D chromatin structures in three stages of breast cancer cells.