GSM5742174[Accession] - GEO DataSets

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Items: 4

Select item 2001912501.

Contribution of astrocytes to familial risk and clinical manifestation of Schizophrenia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL19415 GPL18573 GPL19057
37 Samples

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Accession:: GSE191250

ID:: 200191250

PubMed Full text in PMC Similar studies

Select item 2001912482.

Gene expression analysis of astrocytes differentiated from iPS cells generated from monozygotic twins discordant for schizophrenia

(Submitter supplied) Previous studies have implicated several brain cell types in schizophrenia, but the genetic impact of astrocytes is unknown. Considering their high complexity in humans, astrocytes are likely key determinants of neurodevelopmental diseases. Human induced pluripotent stem cell (hiPSC) -derived astrocytes differentiated from five monozygotic twin pairs discordant for schizophrenia and five healthy subjects were studied for alterations related to high genetic risk and clinical manifestation of SCZ in astrocyte transcriptomics.