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Items: 4

1.

SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia [ChIP-Seq]

(Submitter supplied) Histone methyltransferase SETD1A is critical for acute myeloid leukemia (AML) cell survival, but the molecular mechanism driving SETD1A gene regulation remains elusive. To delineate the role of SETD1A, we utilize a protein degrader technology to induce rapid SETD1A degradation in AML cell lines. SETD1A degradation results in immediate downregulation of transcripts associated with DNA repair and heme biosynthesis pathways. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL18460 GPL18573 GPL24676
50 Samples
Download data: BIGWIG
Series
Accession:
GSE190994
ID:
200190994
2.

SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL18573 GPL18460 GPL24676
68 Samples
Download data: BIGWIG
Series
Accession:
GSE189894
ID:
200189894
3.

Illumina HiSeq 1500 (Homo sapiens)

Platform
Accession:
GPL18460
ID:
100018460
4.

SETD1AKO_FKBP-SETD1A_DMSO_HA ChIP-Seq

Organism:
Homo sapiens
Source name:
MOLM-13
Platform:
GPL18460
Series:
GSE189894 GSE190994
Download data: BIGWIG
Sample
Accession:
GSM5737309
ID:
305737309
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db=gds|term=GSM5737309[Accession]|query=1|qty=2|blobid=MCID_667972b68c5d4760e202f9c1|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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