GSM5478681[Accession] - GEO DataSets

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Items: 4

Select item 2001809591.

Oncogenic lncRNAs alter epigenetic memory at a fragile chromosomal site in human cancer cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other

Platform:: GPL11154
13 Samples

Download data: BED, RESULTS

Series

Accession:: GSE180959

ID:: 200180959

PubMed Full text in PMC Similar studies

Select item 2001809382.

Oncogenic lncRNAs alter epigenetic memory at a fragile chromosomal site in human cancer cells [ChIP-seq]

(Submitter supplied) Chromosome instability is a key event in cancer progression. The essential histone H3 variant CENP-A plays a fundamental role in defining centromere identity, structure, and function, but is innately overexpressed in several types of solid cancers. In the cancer background, excess CENP-A is deposited ectopically on chromosome arms, including at the 8q24/cMYC locus, by invading transcription-coupled H3.3 chaperone pathways. more...