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Items: 4

1.

Discovery and functional interrogation of the virus and host RNA interactome of SARS-CoV-2 proteins

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Chlorocebus sabaeus
Type:
Expression profiling by high throughput sequencing; Other
4 related Platforms
159 Samples
Download data: BW
Series
Accession:
GSE173508
ID:
200173508
2.

Discovery and functional interrogation of the virus and host RNA interactome of SARS-CoV-2 proteins [eCLIP]

(Submitter supplied) The coronavirus disease 2019 (COVID-19) pandemic was caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Understanding the molecular functions of SARS-CoV-2 proteins is thus imperative to developing effective antiviral treatments. Here, we use enhanced crosslinking and immunoprecipitation to investigate SARS-CoV-2 protein interactions with viral and host RNAs. SARS-CoV-2 proteins, NSP8 and NSP12, are found to specifically bind to untranslated regions of the RNA viral genome, with NSP12 additionally binding to all transcription regulatory sequences. more...
Organism:
Homo sapiens; Chlorocebus sabaeus
Type:
Other
Platforms:
GPL18769 GPL11154
147 Samples
Download data: BED, BW, TXT
Series
Accession:
GSE173498
ID:
200173498
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

WT_Strep_HMW rep2 IP

Organism:
Homo sapiens
Source name:
BEAS-2B
Platform:
GPL11154
Series:
GSE173498 GSE173508
Download data
Sample
Accession:
GSM5268731
ID:
305268731
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Supplemental Content

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