GSM523725[Accession] - GEO DataSets

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Items: 3

Select item 2000209451.

Effects of DAC treatment

(Submitter supplied) Reversal of gene promoter DNA hypermethylation and associated abnormal gene silencing is an attractive approach to cancer therapy. The DNA methylation inhibitor, decitabine (5-aza-2'-deoxycitidine), is proving efficacious for hematological neoplasms especially at lower, less toxic, doses. Experimentally, high doses induce rapid DNA damage and cytotoxicity, but these may not explain the prolonged time to response seen in patients. more...

Organism:: Homo sapiens

Type:: Expression profiling by array; Methylation profiling by array

4 related Platforms
55 Samples

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Accession:: GSE20945

ID:: 200020945

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000041332.

Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)

(Submitter supplied) This multi-pack (4X44K) formatted microarray represents a compiled view of the human genome as it is understood today. The sequence information used to design this product was derived from a broad survey of well known sources such as RefSeq, Goldenpath, Ensembl, Unigene and others. The resulting view of the human genome covers 41K unique genes and transcripts which have been verified and optimized by alignment to the human genome assembly and by Agilent's Empirical Validation process. more...