GSM5220663[Accession] - GEO DataSets

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Items: 4

Select item 2001942081.

m6A and YTHDF proteins control the subcellular localization of select neuronal mRNAs

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Other

Platform:: GPL24247
44 Samples

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Accession:: GSE194208

ID:: 200194208

PubMed Full text in PMC Similar studies

Select item 2001711992.

m6A and YTHDF proteins control the subcellular localization of select neuronal mRNAs [RNA-seq and DART-seq]

(Submitter supplied) The transport of mRNAs to distal subcellular compartments is an important component of spatial gene expression control in neurons. However, the mechanisms that control mRNA localization in neurons are not completely understood. Here, we identify the abundant base modification, m6A, as a regulator of mRNA localization in neurons. Transcriptome-wide analysis of mRNA localization in neurons following genetic loss of m6A reveals hundreds of transcripts that exhibit altered subcellular localization. more...