GSM5217325[Accession] - GEO DataSets

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Items: 4

Select item 2001710461.

Spo11 generates gaps through concerted cuts at sites of topological stress

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Nakaseomyces glabratus; Saccharomyces cerevisiae; Saccharomyces kudriavzevii

Type:: Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL29940 GPL29941 GPL29937
71 Samples

Download data: TAR, TXT, WIG

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Accession:: GSE171046

ID:: 200171046

PubMed Similar studies

Select item 2001710422.

Spo11 generates gaps through concerted cuts at sites of topological stress [dDSB]

(Submitter supplied) Meiotic recombination is essential for proper meiotic chromosome segregation and fertility, and is initiated by programmed DNA double-strand breaks (DSBs) introduced by Spo11, a eukaryotic homolog of archaeal topoisomerase VIA. Here we report the discovery of hitherto uncharacterized Spo11-induced lesions, small gaps from 34 bp to several hundred bp, which are generated by coordinated pairs of DSBs (double DSBs or dDSBs). more...