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Items: 3

1.

Paternal MTHFR deficiency leads to reproductive decline across generations in association with hypomethylation of young retrotransposons

(Submitter supplied) 5, 10-Methylenetetrahydrofolate reductase (MTHFR) is a crucial enzyme in the folate metabolic pathway with a key role in generating methyl groups. As MTHFR deficiency impacts male fertility and sperm DNA methylation, there is the potential for epimutations to be passed to the next generation. Here, we assessed whether the impact of MTHFR deficiency on testis morphology and sperm DNA methylation is exacerbated across generations. more...
Organism:
Mus musculus
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL17021
21 Samples
Download data: TXT
Series
Accession:
GSE166586
ID:
200166586

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2500 (Mus musculus)

Organism:
Mus musculus
11263 Series
301308 Samples
Download data
Platform
Accession:
GPL17021
ID:
100017021

3.

Mut_G1_P3-4-EG

Organism:
Mus musculus
Source name:
Sperm
Platform:
GPL17021
Series:
GSE166586
Download data: TXT
Sample
Accession:
GSM5075954
ID:
305075954

SRA Run Selector

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db=gds|term=GSM5075954[Accession]|query=1|qty=2|blobid=MCID_678a3a1a2b88aa5f5d1812a3|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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