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Items: 3

1.

Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development

(Submitter supplied) In mammals, translational control plays critical roles during oocyte-to-embryo transition (OET) when transcription ceases. However, the underlying regulatory mechanisms remain challenging to study. Here, using low-input Ribo-seq (Ribo-lite), we investigated translational landscapes during OET using 30-150 mouse oocytes or embryos per stage. Ribo-lite can also accommodate single oocytes. Combining PAIso-seq to interrogate poly(A) tail lengths, we found a global switch of translatome that closely parallels changes of poly(A) tails upon meiotic resumption. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Other
Platforms:
GPL18480 GPL29177
105 Samples
Download data: BW, TXT
Series
Accession:
GSE165782
ID:
200165782
2.

Illumina HiSeq 1500 (Mus musculus)

Platform
Accession:
GPL18480
ID:
100018480
3.

E3_DRB_E2C_smart

Organism:
Mus musculus
Source name:
Preimplantation embryo
Platform:
GPL18480
Series:
GSE165782
Download data: BW
Sample
Accession:
GSM5049862
ID:
305049862
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db=gds|term=GSM5049862[Accession]|query=1|qty=2|blobid=MCID_666b5a5c909a3d46ad7affa5|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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