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Items: 3

1.

HOTTIP reinforces CTCF-defined TAD boundaries by forming R-loops to drive Wnt/b-catenin target gene expression in AML leukemogenesis

(Submitter supplied) HOTTIP lncRNA is highly expressed in acute myeloid leukemia (AML) patients carrying MLL rearrangement and NPM1c+ mutations, and positively correlates with poor patient survival by facilitating formation of leukemic-specific topologically associated domains (TADs) to drive leukemic transcription program. However, the direct mechanism through which HOTTIP accesses and regulates leukemic genome topology remains unknown. more...
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
Platforms:
GPL24676 GPL21290 GPL24247
51 Samples
Download data: BED, H5, MTX, TSV, TXT
Series
Accession:
GSE165049
ID:
200165049

SRA Run Selector

2.

Illumina HiSeq 3000 (Homo sapiens)

Organism:
Homo sapiens
1136 Series
28205 Samples
Download data
Platform
Accession:
GPL21290
ID:
100021290

3.

MYC-3CBS-RH-H3K27me3-ChIP-seq

Organism:
Homo sapiens
Source name:
MOLM13 leukemia cells
Platform:
GPL21290
Series:
GSE165049
Download data: BED
Sample
Accession:
GSM5025275
ID:
305025275

SRA Run Selector

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db=gds|term=GSM5025275[Accession]|query=1|qty=3|blobid=MCID_66fefc0f8991f171ce336931|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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