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Items: 4

1.

DNA replication-timing boundaries separate stable chromosome domains with cell-type-specific functions

(Submitter supplied) Eukaryotic chromosomes replicate in a temporal order known as the replication-timing program. In mammals, replication timing is cell type-specific with at least half the genome switching replication timing during development, primarily in units of 400-800 kilobases ('replication domains;), whose positions are preserved in different cell types, conserved between species, and appear to confine long-range effects of chromosome rearrangements. more...
Organism:
Homo sapiens; Mus musculus
Type:
Other
25 related Platforms
993 Samples
Download data: BAM, BED, BIGWIG, BROADPEAK, NARROWPEAK, PAIR, TSV, TXT
Series
Accession:
GSE51334
ID:
200051334
2.

Evolutionarily conserved replication timing profiles distinguish cell types and predict long range chromatin interaction

(Submitter supplied) Extensive changes in replication timing occur during early mouse development, but their biological significance remains uncertain. To identify evolutionarily conserved features of replication timing and their relationships to epigenetic properties in humans, we profiled replication timing genome-wide in four human embryonic stem cell (hESC) lines, hESC-derived neural precursor cells (NPCs), lymphoblastoid cells, and two independently derived human induced pluripotent stem cell lines (hiPSCs). more...
Organism:
Homo sapiens
Type:
Other
Platform:
GPL9973
13 Samples
Download data: PAIR
Series
Accession:
GSE20027
ID:
200020027
3.

FSU/NimbleGen Human 2.1M Whole Genome Tiling

(Submitter supplied) Build: Hg18, NCBI 36 Protocol: NimbleGen
Organism:
Homo sapiens
4 Series
46 Samples
Download data
Platform
Accession:
GPL9973
ID:
100009973
4.

Replication timing of BG01 ESC

Organism:
Homo sapiens
Source name:
Early-replicating DNA of BG01 ESC (channel 1) Late-replicating DNA of BG01 ESC (channel 2)
Platform:
GPL9973
Series:
GSE20027 GSE51334
Download data: PAIR
Sample
Accession:
GSM500932
ID:
300500932
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Supplemental Content

db=gds|term=GSM500932[Accession]|query=1|qty=3|blobid=MCID_664b83388626ff46af8904b0|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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