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Items: 3

1.

Transient naive reprogramming corrects hiPS cells functionally and epigenetically [WGBS 2]

(Submitter supplied) Cells undergo a major epigenome reconfiguration when reprogrammed to human induced pluripotent stem cells (hiPS cells). However, the epigenomes of hiPS cells and human embryonic stem (hES) cells differ significantly, which affects hiPS cell function. These differences include epigenetic memory and aberrations that emerge during reprogramming, for which the mechanisms remain unknown. Here we characterized the persistence and emergence of these epigenetic differences by performing genome-wide DNA methylation profiling throughout primed and naive reprogramming of human somatic cells to hiPS cells. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platforms:
GPL18460 GPL18573 GPL24676
21 Samples
Download data: CGMAP
Series
Accession:
GSE160933
ID:
200160933
2.

Illumina HiSeq 1500 (Homo sapiens)

Platform
Accession:
GPL18460
ID:
100018460
3.

RL414: Day_13_Naive_32F

Organism:
Homo sapiens
Source name:
Human reprogramming intermediate cells
Platform:
GPL18460
Series:
GSE160933
Download data: CGMAP
Sample
Accession:
GSM4886713
ID:
304886713
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