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Items: 4

1.

PRC1 drives Polycomb-mediated gene repression by controlling transcription initiation and burst frequency [ChIP-seq]

(Submitter supplied) The Polycomb repressive system plays a fundamental role in controlling gene expression during mammalian development. To achieve this, Polycomb repressive complexes 1 and 2 (PRC1 and PRC2) bind target genes and use histone modification-dependent feedback mechanisms to form Polycomb chromatin domains and repress transcription. The interrelatedness of PRC1 and PRC2 activity at these sites has made it difficult to discover the specific components of Polycomb chromatin domains that drive gene repression and to understand mechanistically how this is achieved. more...
Organism:
Drosophila melanogaster; Homo sapiens; Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL25537 GPL19415
154 Samples
Download data: BED, BW
Series
Accession:
GSE159398
ID:
200159398
2.

PRC1 drives Polycomb-mediated gene repression by controlling transcription initiation and burst frequency

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila melanogaster; Homo sapiens; Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL25537 GPL19415
175 Samples
Download data: BW
Series
Accession:
GSE159400
ID:
200159400
3.

Illumina NextSeq 500 (Homo sapiens; Mus musculus)

Organism:
Homo sapiens; Mus musculus
93 Series
1635 Samples
Download data
Platform
Accession:
GPL19415
ID:
100019415
4.

RING1AKO.RING1BAID_PolII_XInput_IAA_8h_rep3

Organism:
Homo sapiens; Mus musculus
Source name:
Mouse embryonic stem cells with human HEK293T cells spike-in, auxin-treated (8h IAA)
Platform:
GPL19415
Series:
GSE159398 GSE159400
Download data
Sample
Accession:
GSM4829012
ID:
304829012
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