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Items: 3

1.

Molecular basis of CTCF binding polarity in genome folding

(Submitter supplied) Current models propose that boundaries of mammalian topologically associating domains (TADs) arise from the ability of the CTCF protein to stop extrusion of chromatin loops by cohesin. While the orientation of CTCF motifs determines which pairs of CTCF sites preferentially stabilize loops, the molecular basis of this polarity remains mysterious. Here we report that CTCF positions cohesin but does not control its overall binding dynamics on chromatin by single molecule live imaging. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Other
Platform:
GPL19057
161 Samples
Download data: BED, COOL, FASTA, TXT
Series
Accession:
GSE156868
ID:
200156868
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

ENHIC3; Hi-C_CTCF-AID_auxin2days_rep1

Organism:
Mus musculus
Source name:
mouse ES cells, line EN52.9.1
Platform:
GPL19057
Series:
GSE156868
Download data: COOL
Sample
Accession:
GSM4745687
ID:
304745687
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db=gds|term=GSM4745687[Accession]|query=1|qty=2|blobid=MCID_672fa5fdb084802e753a2d8f|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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