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Items: 3

1.

Activation of endogenous retroviruses during brain development causes neuroinflammation

(Submitter supplied) Endogenous retroviruses (ERVs) make up a large fraction of mammalian genome and are thought to contribute to human disease, including brain disorders. Aberrant activation of ERVs constitute a potential trigger for neuroinflammation, but mechanistic insight into this phenomenon remains unclear. Using CRISPR/Cas9-based gene disruption of the epigenetic co-repressor protein Trim28, we found a dynamic H3K9me3-dependent regulation of ERVs in proliferating neural progenitor cells (NPCs), but not in adult neurons. more...
Organism:
Mus musculus
Type:
Other; Expression profiling by high throughput sequencing
Platforms:
GPL19057 GPL24247
38 Samples
Download data: BW, CSV, MTX, TSV, TXT
Series
Accession:
GSE154196
ID:
200154196
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

MJ5_Emx64ctx_Ctl_S2

Organism:
Mus musculus
Source name:
MJ5_Emx64ctx_Ctl_S2_I3
Platform:
GPL24247
Series:
GSE154196
Download data: MTX, TSV
Sample
Accession:
GSM4665777
ID:
304665777
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db=gds|term=GSM4665777[Accession]|query=1|qty=2|blobid=MCID_66ff2b8275ef1969294fc939|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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