GSM456499[Accession] - GEO DataSets

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Items: 3

Select item 2000182781.

IGH analysis in pro-B cells with H3K4me3, H3K4me2 and H3K9ac

(Submitter supplied) STAT5 and IL-7 signaling are thought to control B-lymphopoiesis by regulating key transcription factor genes and activating VH gene segments at the Igh locus. Using conditional mutagenesis, we demonstrate that transgenic Bcl2 expression rescued the development of Stat5-deleted pro-B cells by compensating for the loss of Mcl-1. Ebf1 and Pax5 expression as well as VH recombination were normal in Bcl2-rescued pro-B cells lacking STAT5 or IL-7Ra. more...

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by genome tiling array

Platforms:: GPL9295 GPL9296
9 Samples

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Accession:: GSE18278

ID:: 200018278

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000092962.

GenAu MB BCELL v4.0

(Submitter supplied) genomic regions of potential pax5 target genes from mm8 including IGH and surrounding genes isothermal tiling oligos at 100bp Native NimbelGen files (ndf, pos) linked below as supplementary files. Protocol: as described in www.nimblegen.com