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Items: 3

1.

HDAC4 controls senescence and aging by safeguarding the epigenetic identity and  ensuring the genomic integrity

(Submitter supplied) Purpose: Define the epigenetic program of HDAC4 Outcome: HDAC4 controls the H3K27me3 of repetitive elements of retroviral origin (ERVs) and the H3K27 deacetylation of typical and super-enhancers found to be activated during senescence. The former response is due to the remodeling of the chromatin that sorrounds ERVs, while the latter is directly mediated by HDAC4 binding to the chromatin and the local deacetylation.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL11154
7 Samples
Download data: BW
Series
Accession:
GSE149644
ID:
200149644
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

SK-LMS-1_H3K27ac WT ChIP [Cr_S12]

Organism:
Homo sapiens
Source name:
SK-LMS-1
Platform:
GPL11154
Series:
GSE149644
Download data: BW
Sample
Accession:
GSM4506464
ID:
304506464
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