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Items: 3

1.

The landscape of RNA Pol II binding reveals a step-wise transition during ZGA

(Submitter supplied) Zygotic genome activation (ZGA) is the first transcription event in life. However, it is unclear how RNA polymerase is engaged in initiating ZGA in mammals. Here, by developing small-scale Tn5-assisted chromatin cleavage with sequencing (Stacc–seq), we investigated the landscapes of RNA polymerase II (Pol II) binding in mouse embryos. We found that Pol II undergoes ‘loading’, ‘pre-configuration’, and ‘production’ during the transition from minor ZGA to major ZGA. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL17021 GPL21273
116 Samples
Download data: BEDGRAPH, TXT
Series
Accession:
GSE135457
ID:
200135457
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

mES_1100_spk_Ctrl_rep3

Organism:
Mus musculus
Source name:
Embryonic stem cell
Platform:
GPL21273
Series:
GSE135457
Download data: BEDGRAPH
Sample
Accession:
GSM4476411
ID:
304476411
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