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Items: 4

1.

IL13 and CCL2 Drive Disease in an Inflammatory Subset of Scleroderma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array
Platforms:
GPL7202 GPL6480
44 Samples
Download data: GPR
Series
Accession:
GSE24410
ID:
200024410
2.

IL13 and CCL2 Drive Disease in an Inflammatory Subset of Scleroderma [cGVHD]

(Submitter supplied) Scleroderma is a lethal and currently irreversible autoimmune disease characterized by widespread tissue fibrosis and vasculopathy. Using cross-species comparative gene expression profiling we show that murine sclerodematous graft-versus-host disease (sclGVHD) approximates an “inflammatory” subset of human scleroderma and that both diseases demonstrate activation of the IL13 cytokine pathway. We report that both host myeloid cells expressing type I and II activated macrophage markers and graft T-cells produce IL13 and that host mice deficient in either IL13 or IL4Rα, an IL13 signal transducer, are protected from disease. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL7202
28 Samples
Download data: GPR
Series
Accession:
GSE17914
ID:
200017914
3.

Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Probe Name version)

(Submitter supplied) Designed to truly represent all known genes in the mouse genome and their resulting transcripts, Agilent's Whole Mouse Genome Oligo – 4X44K microarray is comprised of 41,534 60-mer oligonucleotide probes representing over 41,000 mouse genes and transcripts. Content for this microarray was generated from leading public databases, including RefSeq, RIKEN, NIA, Ensembl, RIKEN, UCSC Goldenpath, and Unigene. more...
Organism:
Mus musculus
16 DataSets
653 Series
1 Related Platform
10672 Samples
Download data
Platform
Accession:
GPL7202
ID:
100007202
4.

6152 B10.D2 -> balb rag2-/- (new)

Organism:
Mus musculus
Source name:
B10.D2 -> balb rag2-/- (channel 1) Universal Mouse Reference (channel 2)
Platform:
GPL7202
Series:
GSE17914 GSE24410
Download data: GPR
Sample
Accession:
GSM447493
ID:
300447493
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Supplemental Content

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