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Items: 4

1.

BCL11A promotes myeloid leukemogenesis by abrogating the transcriptional activity of PU.1

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array
Platforms:
GPL11180 GPL16417
16 Samples
Download data: CEL, TDF
Series
Accession:
GSE147798
ID:
200147798
2.

BCL11A promotes myeloid leukemogenesis by abrogating the transcriptional activity of PU.1 [array]

(Submitter supplied) The transcriptional repressor Bcl11a is involved in hematological malignancies, B-cell development and fetal to adult hemoglobin switching, however, the molecular mechanism how Bcl11a promotes development of myeloid leukemia remains largely unknown. We found that Bcl11a cooperates with the pseudokinase Trib1 in AML development. Bcl11a promotes proliferation of Trib1-expressing AML cells both in vitro and in vivo. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL11180
12 Samples
Download data: CEL
Series
Accession:
GSE147797
ID:
200147797
3.

[HT_MG-430_PM] Affymetrix HT MG-430 PM Array Plate

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Protocol: see manufacturer's web site
Organism:
Mus musculus
13 DataSets
285 Series
9 Related Platforms
6973 Samples
Download data
Platform
Accession:
GPL11180
ID:
100011180
4.

TB14-1

Organism:
Mus musculus
Source name:
AML cell line expressing Trib1 and Bcl11a
Platform:
GPL11180
Series:
GSE147797 GSE147798
Download data: CEL
Sample
Accession:
GSM4446327
ID:
304446327
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Supplemental Content

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