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Items: 4

1.

mTORC1 and B cell survival signal regulate formation of memory precursors in the germinal center

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18480
24 Samples
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Series
Accession:
GSE147096
ID:
200147096
2.

mTORC1 and B cell survival signal regulate formation of memory precursors in the germinal center [2]

(Submitter supplied) A still unanswered question is what drives the small fraction of activated germinal center (GC) B cells that survive to become long-lived quiescent memory B cells. We found here that a small population of light zone GC cells (CD38intBcl6hi/intEfnb1+) with lower mTORC1 activity favored the memory B cell fate. Constitutively high mTORC1 activity led to defects in formation of the CD38intBcl6hi/intEfnb1+ cells; conversely, decreasing mTORC1 activity resulted in relative enrichment of this memory-prone GC population over the recycling-prone one. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18480
16 Samples
Download data: TXT
Series
Accession:
GSE147095
ID:
200147095
3.

Illumina HiSeq 1500 (Mus musculus)

Platform
Accession:
GPL18480
ID:
100018480
4.

Fraction 3#1

Organism:
Mus musculus
Source name:
Fraction 3 B cells
Platform:
GPL18480
Series:
GSE147095 GSE147096
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Sample
Accession:
GSM4417000
ID:
304417000
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Supplemental Content

db=gds|term=GSM4417000[Accession]|query=1|qty=2|blobid=MCID_666eac24909a3d46adbe1865|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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