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Items: 3

1.

The SAM domain-containing protein 1 (SAMD1) acts as a repressive chromatin regulator at unmethylated CpG islands

(Submitter supplied) CpG-islands (CGIs) are key regulatory DNA elements at most promoters, but how they influence the chromatin status and transcription remains elusive. Here we identify and characterize SAMD1 (SAM domain-containing protein 1) as an unmethylated CGI-binding protein. SAMD1 possesses an atypical winged-helix domain that directly recognizes unmethylated CpG-containing DNA via simultaneous interactions with both the major and the minor groove. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL21626 GPL18480
55 Samples
Download data: BW, TXT
Series
Accession:
GSE144396
ID:
200144396
2.

Illumina HiSeq 1500 (Mus musculus)

Platform
Accession:
GPL18480
ID:
100018480
3.

RNA-Seq WT repl3

Organism:
Mus musculus
Source name:
E14TG2a
Platform:
GPL18480
Series:
GSE144396
Download data
Sample
Accession:
GSM4287337
ID:
304287337
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Supplemental Content

db=gds|term=GSM4287337[Accession]|query=1|qty=2|blobid=MCID_667105ecce9c6e4cac366655|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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