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Items: 4

1.

Identification of genes upregulated and downregulated in transformed cells (TCs) derived upon Atoh8 depletion

(Submitter supplied) Upon Atoh8 downregulation by shRNA in MEFs, KRas512D mutation c-Myc over-expression and depletion of p53 were induced in mouse embryonic fibroblasts. After 10 passages, cells were collected and RNA extracted.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL17021
6 Samples
Download data: TXT
Series
Accession:
GSE143593
ID:
200143593
2.

The comparative roadmaps of reprogramming and transformation unveiled that cellular plasticity is broadly controlled by Bcl11b and Atoh8

(Submitter supplied) Coordinated changes of cellular plasticity and cellular identity are critical for pluripotent reprogramming and oncogenic transformation. However, the sequences of cellular/molecular events that orchestrate these intermingled modifications have never been comparatively dissected. Here, we deconvoluted the cellular trajectories of reprogramming (via Oct4/Sox2/Klf4/c-Myc) and transformation (via Ras/c-Myc) at the single-cell resolution and revealed how the two processes intersect prior to bifurcate. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
59 Samples
Download data: BEDGRAPH, MTX, TSV, TXT, XLS
Series
Accession:
GSE137050
ID:
200137050
3.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
4.

TC sh#Control rep3

Organism:
Mus musculus
Source name:
mouse embryonic fibroblasts
Platform:
GPL17021
Series:
GSE137050 GSE143593
Download data
Sample
Accession:
GSM4263590
ID:
304263590
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db=gds|term=GSM4263590[Accession]|query=1|qty=2|blobid=MCID_6625624de53bb618e19ba478|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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