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Items: 4

1.

Non-Canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
45 Samples
Download data: BROADPEAK, BW, NARROWPEAK
Series
Accession:
GSE143474
ID:
200143474
2.

Non-Canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function [ChIP-Seq]

(Submitter supplied) Mammalian cells respond to insufficient oxygen through transcriptional regulators called hypoxia-inducible factors (HIFs). Although transiently protective, prolonged HIF activity drives distinct pathological responses in different tissues. Using a model of chronic HIF1a accumulation in pluripotent-stem-cell-derived oligodendrocyte progenitors (OPCs), we demonstrate that HIF1a activates non-canonical targets to impair generation of oligodendrocytes from OPCs. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL19057 GPL17021 GPL21103
25 Samples
Download data: BROADPEAK, BW, NARROWPEAK
Series
Accession:
GSE143472
ID:
200143472
3.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
4.

Vhl_H3K27Ac_ChIP_A

Organism:
Mus musculus
Source name:
Oligodendrocyte progenitor cells (OPCs)
Platform:
GPL17021
Series:
GSE143472 GSE143474
Download data: BROADPEAK, BW
Sample
Accession:
GSM4260072
ID:
304260072
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Supplemental Content

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