GSM4254167[Accession] - GEO DataSets

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Items: 4

Select item 2001431511.

The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens; Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array

4 related Platforms
39 Samples

Download data: BED, CEL

Series

Accession:: GSE143151

ID:: 200143151

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001431482.

The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition [HTS]

(Submitter supplied) Endothelial cells play an important role in maintenance of the vascular system and the repair after injury. Under pro-inflammatory conditions, endothelial cells can acquire a mesenchymal phenotype by a process named endothelial-to-mesenchymal transition (EndMT), which affects the functional properties of endothelial cells. Here, we investigated the epigenetic control of EndMT. We show that the histone demethylase JMJD2B is induced by EndMT promoting pro-inflammatory and hypoxic conditions. more...