GEO DataSets

(Submitter supplied) We hypothesized that there are distinct signatures in chromatin of circulating CD8+ T cells depending on their response to anti-PD-1 therapy due to their long-term interaction with the internal stimuli, such as with tumor and its microenvironment, and external stimuli, such as with infectious diseases. To identify unique chromatin regions predicting the clinical outcome of PD-1 therapy, we performed an assay for transposase-accessible chromatin sequencing (ATAC-seq) using blood samples of patients enrolled in PD-1 therapy. more...

Organism:

Homo sapiens

Type:

Genome binding/occupancy profiling by high throughput sequencing

Platform:

GPL18573

32 Samples

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