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Items: 4

1.

Intra-Vk Cluster Recombination Shapes the Ig Kappa Locus Repertoire

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Other; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL16417 GPL21626 GPL15520
69 Samples
Download data: BW
Series
Accession:
GSE140677
ID:
200140677
2.

Intra-Vk Cluster Recombination Shapes the Ig Kappa Locus Repertoire [END-seq]

(Submitter supplied) During V(D)J recombination RAG proteins introduce DNA double strand breaks (DSBs) adjacent to conserved recombination signal sequences (RSS) that contain either 12- or 23-nucleotide spacer regions. Coordinated cleavage following the “12/23” rule predicts that DSBs at variable (V) gene segments should not exceed the level of breakage at joining (J) segments, thereby ensuring that V regions do not engage in undesirable recombination events with one another. more...
Organism:
Mus musculus
Type:
Other
Platform:
GPL21626
19 Samples
Download data: BW
Series
Accession:
GSE140635
ID:
200140635
3.

NextSeq 550 (Mus musculus)

Platform
Accession:
GPL21626
ID:
100021626
4.

END_seq_PB_DELJK_REP2

Organism:
Mus musculus
Source name:
Abelson-transformed pre-B cell
Platform:
GPL21626
Series:
GSE140635 GSE140677
Download data: BW
Sample
Accession:
GSM4176067
ID:
304176067
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