GSM4145060[Accession] - GEO DataSets

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Items: 4

Select item 2001403151.

Trib1 promotes acute myeloid leukemia progression by modulating transcriptional programs of Hoxa9

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL11180 GPL16417
15 Samples

Download data: CEL, TDF

Series

Accession:: GSE140315

ID:: 200140315

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001396412.

Trib1 promotes acute myeloid leukemia progression by modulating transcriptional programs of Hoxa9 [array]

(Submitter supplied) The pseudokinase Trib1 functions as a myeloid oncogene that recruits E3 ubiquitin ligase COP1 to C/EBPa, and interacts with MEK1 to enhance ERK phosphorylation. Close genetic interaction between Trib1 and Hoxa9 has been observed in myeloid leukemogenesis as Trib1 overexpression significantly accelerates Hoxa9-induced leukemia onset. Yet the mechanism how Trib1 functionally modulates Hoxa9 transcription activity is unclear. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Platform:: GPL11180
8 Samples

Download data: CEL

Series

Accession:: GSE139641

ID:: 200139641

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000111803.

[HT_MG-430_PM] Affymetrix HT MG-430 PM Array Plate

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Protocol: see manufacturer's web site