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Items: 3

1.

Muscle specific MyD88-/- confers a sexual dimorphism protecting female mice from inactivity-induced fat accumulation

(Submitter supplied) We demonstrate whole body inflammation (miR146a-/-) exacerbated inactivity-induced fat gain and glucose dysregulation, while muscle specific MyD88 KO mitigated these outcomes in female mice. Higher gene expression of Igf1 and decreased expression of Ip6k3 in muscle of MyD88 KO female mice may explain enhancement of glucose uptake in the soleus. Whereas protection from fat accumulation may be related to visceral fat gene changes in adipose tissue expansion (Prc1↓, Gulp1↑, Anxa2↓, Cav2↓, EHD1↓), adipose beiging (Fgf10↑), metainflammation (Hmox1↓), and genes involved in perfusion. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
16 Samples
Download data: TXT
Series
Accession:
GSE138940
ID:
200138940
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

16149X13 139-V

Organism:
Mus musculus
Source name:
Visceral Fat
Platform:
GPL24247
Series:
GSE138940
Download data
Sample
Accession:
GSM4123965
ID:
304123965
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db=gds|term=GSM4123965[Accession]|query=1|qty=2|blobid=MCID_661e075d610dde48c43642dc|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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