GSM4115957[Accession] - GEO DataSets

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Items: 4

Select item 2001386751.

A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platform:: GPL20301
21 Samples

Download data: NARROWPEAK

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Accession:: GSE138675

ID:: 200138675

Select item 2001386732.

A critical but divergent role of PRDM14 in human primordial germ cell fate revealed by inducible degrons [RNA-seq]

(Submitter supplied) PRDM14 is a crucial regulator of mouse primordial germ cells (mPGC), epigenetic reprogramming and pluripotency, but its role in the evolutionarily divergent regulatory network of human PGCs (hPGCs) remains unclear. Besides, a previous knockdown study indicated that PRDM14 might be dispensable for human germ cell fate. Here, we decided to use inducible degrons for a more rapid and comprehensive PRDM14 depletion. more...