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Items: 4

1.

Heat Shock Factor 1 (HSF1) acquires transcriptional competence under 17b-estradiol in ERa-positive breast cancer cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL18460 GPL16791
8 Samples
Download data: BED, TXT
Series
Accession:
GSE137560
ID:
200137560
2.

Heat Shock Factor 1 (HSF1) acquires transcriptional competence under 17b-estradiol in ERa-positive breast cancer cells [ChIP-seq]

(Submitter supplied) Heat Shock Transcription Factor 1 (HSF1) is a well-known regulator of gene expression during acute environmental stress that enables the cells to survive. Its high level in estrogen receptor-positive breast cancer patients correlated with a worse prognosis. Here, we demonstrated that 17β-estradiol (E2) as well as bisphenol A (BPA) and propyl pyrazole triol (PPT, ERα agonist) led to HSF1 phosphorylation on S326 in ERα positive mammary breast cancer cells, but not in ERα-negative ones. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18460
5 Samples
Download data: BED, TXT
Series
Accession:
GSE137558
ID:
200137558
3.

Illumina HiSeq 1500 (Homo sapiens)

Platform
Accession:
GPL18460
ID:
100018460
4.

ChIP-seq_Input_sample

Organism:
Homo sapiens
Source name:
input sample (mix of all treatments)
Platform:
GPL18460
Series:
GSE137558 GSE137560
Download data
Sample
Accession:
GSM4081758
ID:
304081758
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Supplemental Content

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