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Items: 4

1.

Dynamic 3D chromosomal landscapes in acute leukemia [Hi-C]

(Submitter supplied) Background: Disruptions of 3D chromatin architecture can alter the activity of topologically associated domains (TADs), rewire enhancer-promoter interactions and thus significantly impact gene regulatory programs. Recently, such disruptions have been implicated in tumorigenesis, highlighting the need for a deeper understanding of their detailed role. Methods: T-ALL primary samples and prototypical cell lines as well as healthy T cell counterparts were profiled by in-situ Hi-C, RNA-Seq and CTCF ChIP-Seq. more...
Organism:
Homo sapiens
Type:
Other
Platforms:
GPL24676 GPL16791 GPL20301
20 Samples
Download data: BED
Series
Accession:
GSE134761
ID:
200134761
2.

Dynamic 3D chromosomal landscapes in acute leukemia

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other
4 related Platforms
59 Samples
Download data: BED, TSV
Series
Accession:
GSE115896
ID:
200115896
3.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
4.

ETP-ALL1 (Hi-C)

Organism:
Homo sapiens
Source name:
Peripheral blood primary T-ALL cells
Platform:
GPL24676
Series:
GSE115896 GSE134761
Download data: BED
Sample
Accession:
GSM3967122
ID:
303967122
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Supplemental Content

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